Look at the p adic-valuation of Harmonic sums. For 2-valuation the denominator contains a power of 2 which equals the highest power of 2 less than
When you take common denominators and compute the numerator- you see that all terms except this power of 2 will gives even contributions and this terms gives an odd contribution. Hence the numerator is odd.
What do we know about evaluations for other primes?